.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J06B_Immunoglobulins.J06BB12_EncephalitisTickBorneImmunoglobu.EncephalitisTickBorneImmunoglobu .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J06B_Immunoglobulins.J06BB12_EncephalitisTickBorneImmunoglobu.EncephalitisTickBorneImmunoglobu| name: | EncephalitisTickBorneImmunoglobulin |
| ATC code: | J06BB12 | route: | intramuscular |
| n-compartments | 2 |
Tick borne encephalitis immunoglobulin is a human immunoglobulin preparation derived from plasma of donors immunized against the tick-borne encephalitis (TBE) virus. It was used as a post-exposure prophylactic therapy for TBE infection, particularly in endemic regions. Due to risk of antibody-dependent enhancement and lack of evidence for efficacy, its use has been discontinued and is not currently approved in most countries.
No published pharmacokinetic studies specific to tick borne encephalitis immunoglobulin (ATC J06BB12) could be located. As such, PK parameters are estimated based on data from similar human immunoglobulin G intravenous (IVIg) products administered to healthy adults.