.Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J07A_BacterialVaccines.J07AC01_AnthraxAntigen.AnthraxAntigen .Pharmacolibrary.Drugs.J_AntiinfectivesForSystemicUse.J07A_BacterialVaccines.J07AC01_AnthraxAntigen.AnthraxAntigen| name: | AnthraxAntigen |
| ATC code: | J07AC01 | route: | intramuscular |
| n-compartments | 1 |
Anthrax antigen (protective antigen, PA) is the principal immunogenic component of anthrax vaccines used for the prevention of Bacillus anthracis infection (anthrax) in humans. Vaccines containing anthrax antigen are used particularly in high-risk populations, such as military personnel or persons with occupational exposure. Licensed anthrax vaccines (e.g., Anthrax Vaccine Adsorbed, AVA) are approved by regulatory agencies for prophylactic use.
No peer-reviewed population pharmacokinetic studies for the anthrax antigen (protective antigen, PA) in healthy adults, children, elderly, or specific patient groups were identified. Pharmacokinetic estimates below are based on general knowledge of subcutaneous or intramuscular administration of protein antigen vaccines.