.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01A_AlkylatingAgents.L01AA02_Chlorambucil.Chlorambucil .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01A_AlkylatingAgents.L01AA02_Chlorambucil.Chlorambucil| name: | Chlorambucil |
| ATC code: | L01AA02 | route: | oral |
| n-compartments | 1 |
Chlorambucil is an alkylating agent of the nitrogen mustard type, used primarily to treat chronic lymphocytic leukemia, Hodgkin's lymphoma, and other lymphoid malignancies. It acts by inhibiting DNA replication. While it was widely used in the past, its use has been largely replaced by newer agents in some indications, but it remains approved and in use for certain conditions.
Pharmacokinetic parameters reported in adult patients (both sexes) with malignant disease after oral administration. Main parameters from population PK studies and reviews.
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