.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01B_Antimetabolites.L01BC03_Tegafur.Tegafur_1 .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01B_Antimetabolites.L01BC03_Tegafur.Tegafur_1| name: | Tegafur_1 |
| ATC code: | L01BC03_1 | route: | intravenous |
| n-compartments | 2 |
Tegafur is an anticancer prodrug of 5-fluorouracil (5-FU), typically used in combination with other agents such as uracil or gimeracil/oteracil (as UFT or S-1 formulations) for the oral treatment of various solid tumors, including gastrointestinal cancers. While tegafur is not widely used as monotherapy today, its combinational forms remain approved and in clinical use, primarily in Asia.
Pharmacokinetic parameters obtained in cancer patients after intravenous bolus dose, assessed using a two-compartment model.
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