.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01D_CytotoxicAntibioticsAndRelatedSubstances.L01DB02_Daunorubicin.Daunorubicin .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01D_CytotoxicAntibioticsAndRelatedSubstances.L01DB02_Daunorubicin.Daunorubicin| name: | Daunorubicin |
| ATC code: | L01DB02 | route: | intravenous |
| n-compartments | 2 |
Daunorubicin is an anthracycline antibiotic antineoplastic agent used primarily in the treatment of acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL). It works by intercalating DNA and inhibiting topoisomerase II, leading to inhibition of DNA replication and repair. The drug is approved and used today, mostly in combination chemotherapy protocols for leukemia.
Pharmacokinetic parameters reported in adult patients with acute myeloid leukemia after intravenous infusion of daunorubicin.
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