name: | Pacritinib |
ATC code: | L01EJ03 | route: | oral |
n-compartments | 2 |
Pacritinib is an oral, selective inhibitor of Janus-associated kinases JAK2 and FLT3 used for the treatment of myelofibrosis, particularly in patients with thrombocytopenia. It is approved for use in several countries for adults with intermediate- or high-risk primary or secondary myelofibrosis.
Population pharmacokinetic parameters reported in adult patients with myelofibrosis, following oral administration as part of clinical development.