name: | Momelotinib |
ATC code: | L01EJ04 | route: | oral |
n-compartments | 2 |
Momelotinib is an orally bioavailable, small molecule inhibitor of Janus kinase 1 and 2 (JAK1/2) and activin A receptor type I (ACVR1). It is primarily used for the treatment of myelofibrosis, a type of myeloproliferative neoplasm, and is approved for this indication.
Pharmacokinetic parameters in adult patients with myelofibrosis following oral administration.