name: | Pralsetinib |
ATC code: | L01EX23 | route: | oral |
n-compartments | 2 |
Pralsetinib is an orally administered, selective RET receptor tyrosine kinase inhibitor used for the treatment of RET fusion-positive non-small cell lung cancer (NSCLC) and RET-mutant or RET fusion-positive thyroid cancers. It is approved by the FDA and EMA for these indications.
Pharmacokinetic parameters reported for adult patients with advanced solid tumors, based on population PK analysis.