.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01X_OtherAntineoplasticAgents.L01XX36_Oblimersen.Oblimersen

Information

name:Oblimersen
ATC code:L01XX36
route:intravenous
n-compartments2

Oblimersen is an antisense oligonucleotide designed to target the messenger RNA of the BCL-2 protein, inducing apoptosis in tumor cells by reducing BCL-2 expression. Investigated in several cancers, especially chronic lymphocytic leukemia and melanoma, oblimersen has not gained regulatory approval and is not currently in widespread clinical use.

Pharmacokinetics

Pharmacokinetic parameters estimated from literature, typical oncology intravenous dosing in adults; population: adult cancer patients.

References

    Revisions

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