.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01X_OtherAntineoplasticAgents.L01XX40_OmacetaxineMepesuccinate.OmacetaxineMepesuccinate .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01X_OtherAntineoplasticAgents.L01XX40_OmacetaxineMepesuccinate.OmacetaxineMepesuccinate| name: | OmacetaxineMepesuccinate | |
| ATC code: | L01XX40 | route: | subcutaneous |
| compartments: | 2 | |
| dosage: | 1.25 | mg |
| volume of distribution: | 126 | L |
| clearance: | 11.6 | L/h |
| other parameters in model implementation | ||
Omacetaxine mepesuccinate (also known as homoharringtonine) is an alkaloid antineoplastic agent approved for the treatment of chronic myeloid leukemia (CML) in adults with resistance and/or intolerance to two or more tyrosine kinase inhibitors.
Pharmacokinetics reported in adult patients with chronic or accelerated phase chronic myeloid leukemia receiving subcutaneous administration.