name: | Buserelin |
ATC code: | L02AE01 | route: | subcutaneous |
n-compartments | 2 |
Buserelin is a synthetic analogue of the gonadotropin-releasing hormone (GnRH) used primarily in the treatment of hormone-sensitive cancers such as prostate cancer, endometriosis, and occasionally in assisted reproduction. It acts as a GnRH agonist, causing downregulation of pituitary secretion of gonadotropins and subsequent reduction in sex steroid production. The drug is approved and in current clinical use.
Pharmacokinetic parameters in healthy male volunteers after single subcutaneous administration.