.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L03A_Immunostimulants.L03AX08_PolyIclc.PolyIclc .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L03A_Immunostimulants.L03AX08_PolyIclc.PolyIclc| name: | PolyIclc |
| ATC code: | L03AX08 | route: | intramuscular |
| n-compartments | 1 |
Poly ICLC (polyinosinic-polycytidylic acid stabilized with poly-L-lysine and carboxymethylcellulose) is a synthetic double-stranded RNA used as an immune modulator and adjuvant, primarily for research and investigational purposes in oncology and infectious diseases to stimulate innate immune responses via toll-like receptor 3 (TLR3). It is not approved for routine clinical use.
No pharmacokinetic parameters have been reported in published literature for poly ICLC in humans. The following values are placeholders based on general estimates for large molecular weight biologics administered intramuscularly.