.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L04A_Immunosuppressants.L04AC03_Anakinra.Anakinra_1 .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L04A_Immunosuppressants.L04AC03_Anakinra.Anakinra_1| name: | Anakinra_1 |
| ATC code: | L04AC03_1 | route: | subcutaneous |
| n-compartments | 1 |
Anakinra is a recombinant, non-glycosylated human interleukin-1 receptor antagonist (IL-1Ra) protein used for the treatment of rheumatoid arthritis and other autoinflammatory conditions. Anakinra blocks the biological activity of interleukin-1 by competitively inhibiting its binding to the interleukin-1 type I receptor (IL-1RI), and is approved for use in several countries.
Pharmacokinetic parameters reported for patients with end-stage renal disease (ESRD) receiving subcutaneous anakinra 100 mg.
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