.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L04A_Immunosuppressants.L04AK01_Leflunomide.Leflunomide .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L04A_Immunosuppressants.L04AK01_Leflunomide.Leflunomide| name: | Leflunomide |
| ATC code: | L04AK01 | route: | oral |
| n-compartments | 2 |
Leflunomide is an immunomodulatory agent classified as a disease-modifying antirheumatic drug (DMARD). It works primarily by inhibiting dihydroorotate dehydrogenase, thus blocking pyrimidine synthesis, and is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It is approved and widely used today for these indications.
Pharmacokinetic parameters of leflunomide (its active metabolite A77 1726) in healthy adult volunteers after oral administration.
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