.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AB15_Ketorolac.Ketorolac_1

Information

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the short-term treatment of moderate to severe pain. It is typically administered for post-operative pain management and is not recommended for long-term use due to potential side effects, particularly on the gastrointestinal tract and kidneys. Ketorolac is approved and used in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adults after oral administration.

References

1. Mandema, JW, & Stanski, DR (1996). Population pharmacodynamic model for ketorolac analgesia. Clinical pharmacology and therapeutics 60(6) 619–635. DOI:10.1016/S0009-9236(96)90210-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8988064

2. Pate, J, et al., & Gould, S (2022). Efficacy of outpatient infusion therapy in pediatric patients with postconcussive headaches. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 38(1) 103–108. DOI:10.1007/s00381-021-05383-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34671849

Revisions

• 06/2025 initial generated model