.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AE09_Flurbiprofen.Flurbiprofen

Information

name:Flurbiprofen
ATC code:M01AE09
route:oral
n-compartments2

Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of inflammation and pain associated with conditions such as rheumatoid arthritis and osteoarthritis. It has analgesic, anti-inflammatory, and antipyretic properties. The drug is approved and used in clinical practice for acute and chronic pain management, as well as in the treatment of inflammatory disorders.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects following oral administration.

References

  1. Qayyum, A, et al., & Farooqi, ZU (2011). Determination of pharmacokinetics of flurbiprofen in Pakistani population using modified HPLC method. Journal of chromatographic science 49(2) 108–113. DOI:10.1093/chrsci/49.2.108 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21223634

  2. Lee, YJ, et al., & Lee, SY (2015). Effects of CYP2C9*1/*3 genotype on the pharmacokinetics of flurbiprofen in Korean subjects. Archives of pharmacal research 38(6) 1232–1237. DOI:10.1007/s12272-015-0580-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25712887

  3. Kumpulainen, E, et al., & Kokki, H (2010). Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children. British journal of clinical pharmacology 70(4) 557–566. DOI:10.1111/j.1365-2125.2010.03720.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/20840447

Revisions


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