.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AE14_Dexibuprofen.Dexibuprofen

Information

name:Dexibuprofen
ATC code:M01AE14
route:oral
n-compartments1

Dexibuprofen is the S(+)-enantiomer of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of pain, inflammation, and fever in conditions such as rheumatoid arthritis and osteoarthritis. It is approved and used in Europe and other countries, but not in the United States.

Pharmacokinetics

Pharmacokinetic parameters estimated in healthy adult volunteers after single oral dose administration.

References

  1. Yoon, JS, et al., & Lee, JS (2008). The effects and safety of dexibuprofen compared with ibuprofen in febrile children caused by upper respiratory tract infection. British journal of clinical pharmacology 66(6) 854–860. DOI:10.1111/j.1365-2125.2008.03271.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/19032727

  2. Sánchez-López, E, et al., & García, ML (2017). New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9. Nanomedicine : nanotechnology, biology, and medicine 13(3) 1171–1182. DOI:10.1016/j.nano.2016.12.003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27986603

  3. Mandal, U, et al., & Pal, TK (2008). Bioequivalence study of two formulations containing 400 mg dexibuprofen in healthy Indian subjects. Arzneimittel-Forschung 58(7) 342–347. DOI:10.1055/s-0031-1296517 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18751500

Revisions


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