.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AE56_NaproxenAndMisoprostol.NaproxenAndMisoprostol .Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AE56_NaproxenAndMisoprostol.NaproxenAndMisoprostol| name: | NaproxenAndMisoprostol |
| ATC code: | M01AE56 | route: | oral |
| n-compartments | 1 |
Naproxen and misoprostol is a fixed-dose combination drug used for the treatment of osteoarthritis and rheumatoid arthritis in patients at risk of developing gastrointestinal ulcers from nonsteroidal anti-inflammatory drug (NSAID) use. Naproxen provides anti-inflammatory and analgesic effects, while misoprostol is a prostaglandin analogue used to reduce the risk of NSAID-induced gastric ulcers. The combination is marketed under brand names such as Arthrotec and is approved for medical use.
Estimated pharmacokinetic parameters for typical adult population after oral administration of the fixed-combination tablet. No published PK population model for the fixed combination was found; estimates are based on data for individual components.