.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AG01_MefenamicAcid.MefenamicAcid

Information

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the treatment of mild to moderate pain, including menstrual pain (dysmenorrhea) and arthritis. It is still approved and used in clinical practice in several countries.

Pharmacokinetics

Pharmacokinetic parameters reported from a study in healthy adult volunteers after a single oral dose.

References

1. Silva, MI, et al., & Halbert, GW (2023). Fed intestinal solubility limits and distributions applied to the Developability classification system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 186 74–84. DOI:10.1016/j.ejpb.2023.03.005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36934829

2. Jo, H, et al., & Tang, W (2021). Model-Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes. CPT: pharmacometrics & systems pharmacology 10(2) 108–118. DOI:10.1002/psp4.12577 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33439535

Revisions

• 06/2025 initial generated model