.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AX21_Diacerein.Diacerein .Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M01A_AntiinflammatoryAndAntirheumaticProductsNonStero.M01AX21_Diacerein.Diacerein| name: | Diacerein |
| ATC code: | M01AX21 | route: | oral |
| n-compartments | 1 |
Diacerein is an anthraquinone derivative with anti-inflammatory and anti-osteoarthritic properties. It is primarily used in the treatment of osteoarthritis, especially in Europe and some other countries. Diacerein acts through inhibition of interleukin-1 and has been used as an alternative to non-steroidal anti-inflammatory drugs (NSAIDs). Its use is approved in some regions but is limited or withdrawn in others due to gastrointestinal side effects.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral administration.
Sharma, A, et al., & Baliga, VP (2008). An open prospective study on postmarketing evaluation of the efficacy and tolerability of diacerein in osteo-arthritis of the knee (DOK). Journal of the Indian Medical Association 106(1) 54–58. PUBMED:https://pubmed.ncbi.nlm.nih.gov/18705272