.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M03C_MuscleRelaxantsDirectlyActingAgents.M03CA01_Dantrolene.Dantrolene

Information

name:Dantrolene
ATC code:M03CA01
route:oral
n-compartments1

Dantrolene is a muscle relaxant primarily used to treat malignant hyperthermia, a life-threatening reaction to certain anesthesia drugs. It is also used in chronic spasticity related to upper motor neuron disorders such as cerebral palsy, stroke, multiple sclerosis, and spinal cord injury. Dantrolene acts on the ryanodine receptor to inhibit calcium release from the sarcoplasmic reticulum in skeletal muscle. It is approved and used clinically today.

Pharmacokinetics

Pharmacokinetic parameters following oral administration in healthy adult volunteers.

References

    Revisions


    Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos