.Pharmacolibrary.Drugs.M_MusculoSkeletalSystem.M03C_MuscleRelaxantsDirectlyActingAgents.M03CA01_Dantrolene.Dantrolene_1

Information

Dantrolene is a muscle relaxant used to treat malignant hyperthermia and spasticity. It acts by inhibiting Ca2+ release in skeletal muscle. It is approved and still used in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported after intravenous administration in adult patients.

References

1. Bateman, RM, et al., & Prandi, E (2016). 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Critical care (London, England) 20(Suppl 2) 94–None. DOI:10.1186/s13054-016-1208-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27885969

Revisions

• 06/2025 initial generated model