.Pharmacolibrary.Drugs.N_NervousSystem.N01B_AnestheticsLocal.N01BB03_Mepivacaine.Mepivacaine .Pharmacolibrary.Drugs.N_NervousSystem.N01B_AnestheticsLocal.N01BB03_Mepivacaine.Mepivacaine| name: | Mepivacaine | |
| ATC code: | N01BB03 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.75 | L |
| clearance: | 6.3 | mL/min/kg |
| other parameters in model implementation | ||
Mepivacaine is an amide-type local anesthetic used primarily for local and regional anesthesia in dental, obstetric, and surgical procedures. It is approved and commonly used today due to its moderate duration of action and favorable safety profile compared to ester-type anesthetics.
Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.
Mossetti, V, et al., & Ivani, G (2012). Local anesthetis and adjuvants in pediatric regional anesthesia. Current drug targets 13(7) 952–960. DOI:10.2174/138945012800675713 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22512395