.Pharmacolibrary.Drugs.N_NervousSystem.N01B_AnestheticsLocal.N01BB04_Prilocaine.Prilocaine

Information

name:Prilocaine
ATC code:N01BB04
route:intravenous
compartments:2
dosage:50mg
volume of distribution:1.7L
clearance:2.84mL/min/kg
other parameters in model implementation

Prilocaine is an amide-type local anesthetic, primarily used for infiltration, nerve block, and intravenous regional anesthesia. It is widely used due to its relatively rapid onset and intermediate duration of action. Prilocaine is approved for medical use and is still in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.

References

  1. O'Brien, L, et al., & Koren, G (2005). A critical review of the topical local anesthetic amethocaine (Ametop) for pediatric pain. Paediatric drugs 7(1) 41–54. DOI:10.2165/00148581-200507010-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15777110

  2. Snoeck, M (2012). Articaine: a review of its use for local and regional anesthesia. Local and regional anesthesia 5 23–33. DOI:10.2147/LRA.S16682 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22915899

Revisions


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