.Pharmacolibrary.Drugs.N_NervousSystem.N01B_AnestheticsLocal.N01BB04_Prilocaine.Prilocaine

Information

Prilocaine is an amide-type local anesthetic, primarily used for infiltration, nerve block, and intravenous regional anesthesia. It is widely used due to its relatively rapid onset and intermediate duration of action. Prilocaine is approved for medical use and is still in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.

References

1. O'Brien, L, et al., & Koren, G (2005). A critical review of the topical local anesthetic amethocaine (Ametop) for pediatric pain. Paediatric drugs 7(1) 41–54. DOI:10.2165/00148581-200507010-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15777110

2. Snoeck, M (2012). Articaine: a review of its use for local and regional anesthesia. Local and regional anesthesia 5 23–33. DOI:10.2147/LRA.S16682 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22915899

Revisions

• 06/2025 initial generated model