.Pharmacolibrary.Drugs.N_NervousSystem.N02A_Opioids.N02AA01_Morphine.Morphine_1

Information

name:Morphine_1
ATC code:N02AA01_1
route:oral
n-compartments2

Morphine is a potent opioid analgesic derived from opium and is primarily used for the relief of moderate to severe pain. It acts as an agonist at the mu-opioid receptor and is widely used in both acute and chronic pain management, including post-surgical, cancer, and palliative care settings. Morphine is an approved drug and is currently utilized globally for its analgesic properties.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult subjects after oral administration.

References

  1. Lugo, RA, & Kern, SE (2002). Clinical pharmacokinetics of morphine. Journal of pain & palliative care pharmacotherapy 16(4) 5–18. DOI:10.1080/j354v16n04_02 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14635822

  2. Lugo, RA, & Kern, SE (2004). The pharmacokinetics of oxycodone. Journal of pain & palliative care pharmacotherapy 18(4) 17–30. DOI:10.1300/j354v18n04_03 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15760805

  3. Thigpen, JC, et al., & Harirforoosh, S (2019). Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children. European journal of drug metabolism and pharmacokinetics 44(5) 591–609. DOI:10.1007/s13318-019-00552-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31006834

Revisions


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