.Pharmacolibrary.Drugs.N_NervousSystem.N02A_Opioids.N02AJ13_TramadolAndParacetamol.TramadolAndParacetamol

Information

name: TramadolAndParacetamol
ATC code: N02AJ13
route: oral
compartments: 2
dosage: 37.5 mg
volume of distribution: 2.7 L
clearance: 0.22 L/h/kg (tramadol)
other parameters in model implementation

Tramadol and paracetamol is a fixed-dose combination analgesic used for the management of moderate to severe pain when treatment with a combination of tramadol, an opioid analgesic, and paracetamol (acetaminophen), a non-opioid analgesic, is appropriate. This drug combination is widely approved and currently used in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after a single oral dose of tramadol 37.5 mg and paracetamol 325 mg.

References

Revisions


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