.Pharmacolibrary.Drugs.N_NervousSystem.N02A_Opioids.N02AJ14_TramadolAndDexketoprofen.TramadolAndDexketoprofen .Pharmacolibrary.Drugs.N_NervousSystem.N02A_Opioids.N02AJ14_TramadolAndDexketoprofen.TramadolAndDexketoprofen| name: | TramadolAndDexketoprofen | |
| ATC code: | N02AJ14 | route: | oral |
| compartments: | 1 | |
| dosage: | 75 | mg |
| volume of distribution: | 3 | L |
| clearance: | 350 | mL/min |
| other parameters in model implementation | ||
Tramadol and dexketoprofen is a fixed-dose combination analgesic medication used for the management of moderate to severe acute pain. Tramadol is an opioid analgesic with additional serotonergic and noradrenergic effects, while dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). The combination provides multimodal pain relief. The fixed-dose combination is approved in the EU and other markets for short-term treatment of moderate to severe acute pain.
Estimated pharmacokinetic parameters for adult healthy volunteers. No direct published population pharmacokinetic model for the combination was found; values were approximated based on published data for individual components and summary pharmacokinetic information from regulatory sources.