name: | Phenazone | |
ATC code: | N02BB01 | route: | oral |
compartments: | 1 | |
dosage: | 900 | mg |
volume of distribution: | 0.6 | L |
clearance: | 2.7 | mL/min/kg |
other parameters in model implementation |
Phenazone (also known as antipyrine) is a non-opioid analgesic and antipyretic formerly used for the relief of pain and fever. It is a pyrazolone derivative. Its use today is rare in many countries, having been largely replaced by safer and more effective agents, though it remains a classic model drug in pharmacokinetics studies due to well-established metabolic pathways.
Pharmacokinetic parameters reported for healthy adult volunteers (mixed sex, typical age 20-40 years) after a single oral dose.