.Pharmacolibrary.Drugs.N_NervousSystem.N02C_AntimigrainePreparations.N02CC02_Naratriptan.Naratriptan

Information

name:Naratriptan
ATC code:N02CC02
route:oral
compartments:1
dosage:2.5mg
volume of distribution:170L
clearance:7.1L/h
other parameters in model implementation

Naratriptan is a selective serotonin 5-HT1B/1D receptor agonist used for the acute treatment of migraine attacks with or without aura in adults. It is approved for use in several countries and is available as oral tablets.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers following single oral dose administration.

References

  1. Eiland, LS, & Hunt, MO (2010). The use of triptans for pediatric migraines. Paediatric drugs 12(6) 379–389. DOI:10.2165/11532860-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21028917

  2. Jhee, SS, et al., & Cutler, NR (2001). Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review. Clinical pharmacokinetics 40(3) 189–205. DOI:10.2165/00003088-200140030-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11327198

Revisions


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