.Pharmacolibrary.Drugs.N_NervousSystem.N02C_AntimigrainePreparations.N02CC07_Frovatriptan.Frovatriptan

Information

name:Frovatriptan
ATC code:N02CC07
route:oral
n-compartments2

Frovatriptan is a selective serotonin (5-HT1B/1D) receptor agonist in the triptan class, used for the acute treatment of migraine attacks with or without aura in adults. It is approved for use in several countries for migraine relief.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers (both sexes, age 18-65), after single oral dose administration.

References

  1. Zheng, H, et al., & Fan, H (2021). Pharmacokinetic Study of Frovatriptan Succinate Tablet After Single and Multiple Oral Doses in Chinese Healthy Subjects. Drug design, development and therapy 15 2961–2968. DOI:10.2147/DDDT.S308958 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34262261

  2. Eiland, LS, & Hunt, MO (2010). The use of triptans for pediatric migraines. Paediatric drugs 12(6) 379–389. DOI:10.2165/11532860-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21028917

  3. Jhee, SS, et al., & Cutler, NR (2001). Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review. Clinical pharmacokinetics 40(3) 189–205. DOI:10.2165/00003088-200140030-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11327198

Revisions


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