name: | Clonidine |
ATC code: | N02CX02 | route: | oral |
n-compartments | 2 |
Clonidine is an alpha-2 adrenergic agonist used for the treatment of hypertension, attention deficit hyperactivity disorder (ADHD), and occasionally for management of withdrawal symptoms or pain. It remains approved and in use for these indications today.
Pharmacokinetic parameters reported for healthy adult volunteers after oral tablet administration.
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Bienert, A, et al., & Grześkowiak, E (2015). Melatonin and clonidine premedication has similar impact on the pharmacokinetics and pharmacodynamics of propofol target controlled-infusions. Journal of clinical pharmacology 55(3) 307–316. DOI:10.1002/jcph.401 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25243731