.Pharmacolibrary.Drugs.N_NervousSystem.N03A_Antiepileptics.N03AG06_Tiagabine.Tiagabine

Information

name:Tiagabine
ATC code:N03AG06
route:oral
n-compartments1

Tiagabine is an anticonvulsant medication primarily used as an adjunctive therapy in the treatment of partial seizures in epilepsy. It works by inhibiting the reuptake of gamma-aminobutyric acid (GABA) in the brain, thereby increasing the availability of this inhibitory neurotransmitter. Tiagabine is approved for clinical use and is typically administered orally.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers receiving single oral doses.

References

  1. Jacob, S, & Nair, AB (2016). An Updated Overview on Therapeutic Drug Monitoring of Recent Antiepileptic Drugs. Drugs in R&D 16(4) 303–316. DOI:10.1007/s40268-016-0148-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27766590

  2. Perucca, E (2005). Pharmacokinetic variability of new antiepileptic drugs at different ages. Therapeutic drug monitoring 27(6) 714–717. DOI:10.1097/01.ftd.0000179847.37965.4e PUBMED:https://pubmed.ncbi.nlm.nih.gov/16404801

Revisions


Generated at 2025-07-20T18:21:09Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos