name: | Tiagabine |
ATC code: | N03AG06 | route: | oral |
n-compartments | 1 |
Tiagabine is an anticonvulsant medication primarily used as an adjunctive therapy in the treatment of partial seizures in epilepsy. It works by inhibiting the reuptake of gamma-aminobutyric acid (GABA) in the brain, thereby increasing the availability of this inhibitory neurotransmitter. Tiagabine is approved for clinical use and is typically administered orally.
Pharmacokinetic parameters reported for healthy adult volunteers receiving single oral doses.
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Perucca, E (2005). Pharmacokinetic variability of new antiepileptic drugs at different ages. Therapeutic drug monitoring 27(6) 714–717. DOI:10.1097/01.ftd.0000179847.37965.4e PUBMED:https://pubmed.ncbi.nlm.nih.gov/16404801