.Pharmacolibrary.Drugs.N_NervousSystem.N04B_DopaminergicAgents.N04BC04_Ropinirole.Ropinirole

Information

name:Ropinirole
ATC code:N04BC04
route:oral
n-compartments1

Ropinirole is a non-ergoline dopamine agonist primarily used in the treatment of Parkinson's disease and restless legs syndrome. It is approved for clinical use in many countries, including the USA and Europe, for both indications.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult male and female volunteers after single oral administration.

References

  1. Kaye, CM, & Nicholls, B (2000). Clinical pharmacokinetics of ropinirole. Clinical pharmacokinetics 39(4) 243–254. DOI:10.2165/00003088-200039040-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11069211

  2. Hattori, N, et al., & Sakamoto, T (2012). Pharmacokinetics and effect of food after oral administration of prolonged-release tablets of ropinirole hydrochloride in Japanese patients with Parkinson's disease. Journal of clinical pharmacy and therapeutics 37(5) 571–577. DOI:10.1111/j.1365-2710.2012.01336.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22390368

  3. Lai, KL, et al., & Lee, WYT (2018). Orally-dissolving film for sublingual and buccal delivery of ropinirole. Colloids and surfaces. B, Biointerfaces 163 9–18. DOI:10.1016/j.colsurfb.2017.12.015 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29268211

Revisions


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