.Pharmacolibrary.Drugs.N_NervousSystem.N05B_Anxiolytics.N05BA05_PotassiumClorazepate.PotassiumClorazepate

Information

name:PotassiumClorazepate
ATC code:N05BA05
route:oral
compartments:1
dosage:15mg
volume of distribution:1.5L
clearance:0.015L/kg/h
other parameters in model implementation

Potassium clorazepate is a benzodiazepine prodrug used primarily as an anxiolytic, anticonvulsant, and for the management of alcohol withdrawal symptoms. It is converted in the body to its active metabolite nordiazepam (desmethyldiazepam). It is approved and used in several countries for anxiety disorders, epilepsy, and adjunct therapy in acute alcohol withdrawal.

Pharmacokinetics

Pharmacokinetic parameters after a single oral dose of 15 mg potassium clorazepate in healthy adult volunteers (mixed sex, age ~18-45 years).

References

    Revisions


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