.Pharmacolibrary.Drugs.N_NervousSystem.N05C_HypnoticsAndSedatives.N05CD01_Flurazepam.Flurazepam .Pharmacolibrary.Drugs.N_NervousSystem.N05C_HypnoticsAndSedatives.N05CD01_Flurazepam.Flurazepam| name: | Flurazepam | |
| ATC code: | N05CD01 | route: | oral |
| compartments: | 2 | |
| dosage: | 30 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 68 | mL/min |
| other parameters in model implementation | ||
Flurazepam is a long-acting benzodiazepine used as a hypnotic for the treatment of insomnia. It acts as a positive allosteric modulator of GABA-A receptors, enhancing inhibitory neurotransmission. While once widely used for insomnia, its use today is limited due to risks of dependence, next-day sedation, and the availability of safer alternatives.
Pharmacokinetic parameters in healthy adult volunteers after a single 30 mg oral dose.