.Pharmacolibrary.Drugs.N_NervousSystem.N05C_HypnoticsAndSedatives.N05CD10_Quazepam.Quazepam .Pharmacolibrary.Drugs.N_NervousSystem.N05C_HypnoticsAndSedatives.N05CD10_Quazepam.Quazepam| name: | Quazepam |
| ATC code: | N05CD10 | route: | oral |
| n-compartments | 2 |
Quazepam is a long-acting benzodiazepine derivative primarily used as a hypnotic for the short-term treatment of insomnia. It acts mainly on the GABA-A receptor to produce sedative, anxiolytic, muscle relaxant, and anticonvulsant effects. Quazepam is currently approved for medical use in some countries; its use has declined in favor of other hypnotics due to concerns over dependence and side effects.
Pharmacokinetics based on healthy adult male volunteers after single oral dose.
Fukasawa, T, et al., & Otani, K (2004). Single oral dose pharmacokinetics of quazepam is influenced by CYP2C19 activity. Therapeutic drug monitoring 26(5) 529–533. DOI:10.1097/00007691-200410000-00011 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15385836