.Pharmacolibrary.Drugs.N_NervousSystem.N05C_HypnoticsAndSedatives.N05CM07_Triclofos.Triclofos

Information

name:Triclofos
ATC code:N05CM07
route:oral
compartments:1
dosage:500mg
volume of distribution:0.6L
clearance:0.08L/kg/h
other parameters in model implementation

Triclofos is a sedative and hypnotic drug, historically used as a sleep-inducing agent, particularly in pediatrics for sedation. It is a prodrug of trichloroethanol, which is the active metabolite responsible for its pharmacological effect. It is rarely used in contemporary medical practice and is largely replaced by safer alternatives.

Pharmacokinetics

Estimated pharmacokinetic parameters for orally administered triclofos, assuming use in pediatric population based on typical clinical protocols. No primary literature reporting human PK values found.

References

    Revisions


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