.Pharmacolibrary.Drugs.N_NervousSystem.N06A_Antidepressants.N06AX23_Desvenlafaxine.Desvenlafaxine

Information

name:Desvenlafaxine
ATC code:N06AX23
route:oral
n-compartments1

Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used in the treatment of major depressive disorder (MDD) in adults. It is approved by the FDA and marketed under the brand name Pristiq.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects after oral administration of a 100 mg tablet.

References

  1. Nichols, AI, et al., & Abbas, R (2018). Population Pharmacokinetics of Desvenlafaxine: Pharmacokinetics in Korean Versus US Populations. Clinical pharmacology in drug development 7(4) 441–450. DOI:10.1002/cpdd.419 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29228473

  2. Dolder, C, et al., & Stump, A (2010). Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients. Drugs & aging 27(8) 625–640. DOI:10.2165/11537140-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20658791

  3. Chen, YX, et al., & Zhong, DF (2015). [The enantioselective pharmacokinetic study of desvenlafaxine sustained release tablet in Chinese healthy male volunteers after oral administration]. Yao xue xue bao = Acta pharmaceutica Sinica 50(4) 486–491. PUBMED:https://pubmed.ncbi.nlm.nih.gov/26223133

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos