.Pharmacolibrary.Drugs.N_NervousSystem.N06A_Antidepressants.N06AX29_Brexanolone.Brexanolone .Pharmacolibrary.Drugs.N_NervousSystem.N06A_Antidepressants.N06AX29_Brexanolone.Brexanolone| name: | Brexanolone | |
| ATC code: | N06AX29 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 900 | mg |
| volume of distribution: | 198 | L |
| clearance: | 1 | liter/h |
| other parameters in model implementation | ||
Brexanolone is a neuroactive steroid and a positive allosteric modulator of GABA-A receptors, used for the treatment of postpartum depression in adult women. It is currently FDA-approved for this indication and is administered as an intravenous infusion.
Pharmacokinetic parameters reported for adult women with postpartum depression following the recommended clinical intravenous dosing regimen.