.Pharmacolibrary.Drugs.N_NervousSystem.N07B_DrugsUsedInAddictiveDisorders.N07BB03_Acamprosate.Acamprosate .Pharmacolibrary.Drugs.N_NervousSystem.N07B_DrugsUsedInAddictiveDisorders.N07BB03_Acamprosate.Acamprosate| name: | Acamprosate | |
| ATC code: | N07BB03 | route: | oral |
| compartments: | 1 | |
| dosage: | 666 | mg |
| volume of distribution: | 20.0 | L |
| clearance: | 80.0 | mL/min |
| other parameters in model implementation | ||
Acamprosate is a synthetic compound used as an adjunct in the treatment of alcohol dependence to help maintain abstinence. It acts primarily as a modulator of glutamatergic neurotransmission. It is approved in many countries for this indication.
Pharmacokinetic parameters in healthy adult subjects following oral administration with steady-state dosing.
Luo, Z, et al., & Qin, Y (2015). Pharmacokinetics and bioequivalence evaluation of acamprosate calcium tablets in healthy Chinese volunteers. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 79 67–72. DOI:10.1016/j.ejps.2015.09.003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26360834