.Pharmacolibrary.Drugs.P_AntiparasiticProductsInsecticidesAndRepellents.P01B_Antimalarials.P01BF04_ArtesunateSulfaleneAndPy.ArtesunateSulfaleneAndPy .Pharmacolibrary.Drugs.P_AntiparasiticProductsInsecticidesAndRepellents.P01B_Antimalarials.P01BF04_ArtesunateSulfaleneAndPy.ArtesunateSulfaleneAndPy| name: | ArtesunateSulfaleneAndPyrimethamine | |
| ATC code: | P01BF04 | route: | oral |
| compartments: | 1 | |
| dosage: | 200 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 1.2 | L/h/kg |
| other parameters in model implementation | ||
A fixed-dose antimalarial combination used in the treatment of uncomplicated Plasmodium falciparum malaria. Artesunate is a fast-acting artemisinin derivative; sulfalene is a long-acting sulfonamide; pyrimethamine is a dihydrofolate reductase inhibitor. This combination is approved and used in some malaria-endemic regions.
No published population pharmacokinetic model specifically for the fixed-dose combination of artesunate, sulfalene, and pyrimethamine with ATC P01BF04. Parameter estimates are approximated from component data (adults, oral administration, healthy or malaria-infected subjects).