.Pharmacolibrary.Drugs.P_AntiparasiticProductsInsecticidesAndRepellents.P02C_AntinematodalAgents.P02CA06_Fenbendazole.Fenbendazole

Information

name:Fenbendazole
ATC code:P02CA06
route:oral
compartments:1
dosage:50mg
volume of distribution:1.29L
clearance:0.21L/kg/h
other parameters in model implementation

Fenbendazole is a benzimidazole anthelmintic used primarily in veterinary medicine for the treatment and control of gastrointestinal parasites in domestic animals such as dogs, cats, horses, pigs, and cattle. It is not approved for human use but has been studied as an experimental antiparasitic and potential anticancer compound.

Pharmacokinetics

Pharmacokinetic parameters of fenbendazole after single oral administration in healthy adult dogs.

References

  1. Bach, T, et al., & An, G (2021). Population Pharmacokinetic Model of Oxfendazole and Metabolites in Healthy Adults following Single Ascending Doses. Antimicrobial agents and chemotherapy 65(4) –. DOI:10.1128/AAC.02129-20 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33526484

  2. Carreño Gútiez, M, et al., & Tell, LA (2024). Estimation of withdrawal interval recommendations following administration of fenbendazole medicated feed to ring-necked pheasants (. Frontiers in veterinary science 11 1444009–None. DOI:10.3389/fvets.2024.1444009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39144087

Revisions


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