name: | Diethyltoluamide |
ATC code: | P03BX01 | route: | topical |
n-compartments | 1 |
Diethyltoluamide (DEET) is an insect repellent commonly used for the prevention of bites from mosquitoes, ticks, and other biting insects. It is topically applied, primarily for self-protection in areas with vector-borne diseases. DEET is approved and widely used globally for human use on skin or clothing.
Pharmacokinetic data for DEET in humans is limited. Available information suggests DEET is absorbed through the skin after topical application, with a portion undergoing dermal absorption and subsequent metabolism. PK parameters are not routinely reported in published research. The following values are estimated based on limited dermal absorption studies in adults.