.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AA06_Tetryzoline.Tetryzoline .Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AA06_Tetryzoline.Tetryzoline| name: | Tetryzoline | |
| ATC code: | R01AA06 | route: | ocular |
| compartments: | 1 | |
| dosage: | 0.5 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 0.02 | L/kg/h |
| other parameters in model implementation | ||
Tetryzoline (also known as tetrahydrozoline) is an imidazoline derivative used as a topical decongestant for relieving redness in the eyes and nasal congestion. It acts as an alpha-adrenergic agonist, causing vasoconstriction. Tetryzoline is available in over-the-counter ocular (eye drops) and nasal preparations in many countries but systemic/injectable use is not approved.
Estimated pharmacokinetics for healthy adult population based on published data for topical imidazoline decongestants and tetrahydrozoline class due to lack of primary PK studies on tetryzoline.