.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AA12_Fenoxazoline.Fenoxazoline .Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AA12_Fenoxazoline.Fenoxazoline| name: | Fenoxazoline |
| ATC code: | R01AA12 | route: | intranasal |
| n-compartments | 1 |
Fenoxazoline is an imidazoline derivative nasal decongestant used for the symptomatic relief of nasal congestion in conditions such as rhinitis or sinusitis. It acts as an alpha-adrenergic agonist leading to vasoconstriction of nasal blood vessels. The drug is not widely used today and is not approved in some jurisdictions.
No published pharmacokinetic data available for fenoxazoline in humans. The following parameters are estimated based on class similarity with other nasal alpha-adrenergic agonists (e.g., xylometazoline, oxymetazoline) for adult healthy subjects.