.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AD08_Fluticasone.Fluticasone

Information

name:Fluticasone
ATC code:R01AD08
route:intranasal
n-compartments1

Fluticasone is a synthetic corticosteroid with potent anti-inflammatory properties. It is commonly used as a nasal spray for the treatment of allergic rhinitis and as an inhaled medication for asthma and chronic obstructive pulmonary disease (COPD). Fluticasone is approved and widely used today in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following intranasal administration of fluticasone propionate.

References

  1. Wolthers, OD (2013). New patents of fixed combinations of nasal antihistamines and corticosteroids in allergic rhinitis. Recent patents on inflammation & allergy drug discovery 7(3) 223–228. DOI:10.2174/1872213x113079990019 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23862774

  2. Wang, P, et al., & Li, X (2025). Pharmacokinetics and Bioequivalence of 2 Products of Fluticasone Propionate Nasal Spray in Healthy Chinese Subjects. Clinical pharmacology in drug development 14(5) 398–403. DOI:10.1002/cpdd.1507 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39828962

  3. Chen, G, et al., & Wang, J (2025). Bioequivalence Study of 2 Formulations of Fluticasone Nasal Spray in Healthy Chinese Volunteers. Clinical pharmacology in drug development 14(3) 270–275. DOI:10.1002/cpdd.1505 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39789740

Revisions


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