.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AD09_Mometasone.Mometasone

Information

name:Mometasone
ATC code:R01AD09
route:intranasal
n-compartments1

Mometasone is a synthetic corticosteroid with potent anti-inflammatory activity. It is mainly used as a nasal spray for the treatment of allergic rhinitis, and also in inhaled and topical forms to treat asthma and inflammatory skin conditions. Mometasone (as mometasone furoate) is approved and widely used today for these indications.

Pharmacokinetics

Pharmacokinetic parameter estimates for adults following intranasal administration of mometasone furoate nasal spray, based on available pharmacokinetic studies in healthy volunteers.

References

  1. Wolthers, OD (2013). New patents of fixed combinations of nasal antihistamines and corticosteroids in allergic rhinitis. Recent patents on inflammation & allergy drug discovery 7(3) 223–228. DOI:10.2174/1872213x113079990019 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23862774

  2. Meltzer, EO, et al., & Nolop, K (1999). A dose-ranging study of mometasone furoate aqueous nasal spray in children with seasonal allergic rhinitis. The Journal of allergy and clinical immunology 104(1) 107–114. DOI:10.1016/s0091-6749(99)70121-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10400847

Revisions


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