.Pharmacolibrary.Drugs.R_RespiratorySystem.R01B_NasalDecongestantsForSystemicUse.R01BA02_Pseudoephedrine.Pseudoephedrine

Information

Pseudoephedrine is a sympathomimetic drug primarily used as a nasal decongestant for the temporary relief of nasal congestion due to colds, allergies, or sinusitis. It is available over-the-counter in many countries and remains widely used, though its sale is restricted due to its potential use in illicit methamphetamine synthesis.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose of pseudoephedrine hydrochloride.

References

1. Howard, DR, et al., & Agrawala, P (2005). Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults. Current medical research and opinion 21(5) 769–776. DOI:10.1185/030079905x43703 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15969876

Revisions

• 06/2025 initial generated model