.Pharmacolibrary.Drugs.R_RespiratorySystem.R01B_NasalDecongestantsForSystemicUse.R01BA52_PseudoephedrineCombinati.PseudoephedrineCombinati .Pharmacolibrary.Drugs.R_RespiratorySystem.R01B_NasalDecongestantsForSystemicUse.R01BA52_PseudoephedrineCombinati.PseudoephedrineCombinati| name: | PseudoephedrineCombinations |
| ATC code: | R01BA52 | route: | oral |
| n-compartments | 1 |
Pseudoephedrine is a sympathomimetic amine commonly used as a nasal decongestant. It acts by stimulating alpha-adrenergic receptors, leading to vasoconstriction in the nasal mucosa, and is frequently included in combination with antihistamines or analgesics for symptomatic relief of cold, allergy, or sinus congestion. Pseudoephedrine-containing products remain approved and widely available, although some countries regulate their sale due to misuse in illicit synthesis.
Pharmacokinetic parameters for pseudoephedrine in healthy adult volunteers after oral administration of pseudoephedrine-containing combination products.
Howard, DR, et al., & Agrawala, P (2005). Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults. Current medical research and opinion 21(5) 769–776. DOI:10.1185/030079905x43703 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15969876