.Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AB30_Gramicidin.Gramicidin .Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AB30_Gramicidin.Gramicidin| name: | Gramicidin | |
| ATC code: | R02AB30 | route: | oral |
| compartments: | 1 | |
| dosage: | 3 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | L/h |
| other parameters in model implementation | ||
Gramicidin is a mixture of peptide antibiotics produced by Bacillus brevis. It is primarily used topically for the treatment of gram-positive bacterial infections, especially in oropharyngeal conditions (such as sore throat). It is not used systemically because of its toxicity. Gramicidin is still available in some countries as a component of throat lozenges and topical antibiotics.
No published pharmacokinetic parameters found for gramicidin in humans. Systemic pharmacokinetic data is unavailable due to its high toxicity and exclusive topical/oral local use.