.Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AB30_Gramicidin.Gramicidin .Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AB30_Gramicidin.Gramicidin| name: | Gramicidin |
| ATC code: | R02AB30 | route: | oral |
| n-compartments | 1 |
Gramicidin is a mixture of peptide antibiotics produced by Bacillus brevis. It is primarily used topically for the treatment of gram-positive bacterial infections, especially in oropharyngeal conditions (such as sore throat). It is not used systemically because of its toxicity. Gramicidin is still available in some countries as a component of throat lozenges and topical antibiotics.
No published pharmacokinetic parameters found for gramicidin in humans. Systemic pharmacokinetic data is unavailable due to its high toxicity and exclusive topical/oral local use.